Structure of PDB 3gyt Chain A Binding Site BS01
Receptor Information
>3gyt Chain A (length=242) Species:
6248
(Strongyloides stercoralis) [
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YTLSEKDLKELDSIRDSFQCMNEPLDNDQQASTLAKKEHNPTDILNVMDI
TMRRLVKMAKRLGAFNEISEAGKFSLLKGGMIEMLTIRGVTVFNADKGVW
QTPVDGHSQISFNMFDKLRPDIKDTQKKGFLHFFNLLHSDVRKNDLAIDI
IVLMVLFDSKREGLVSQQDKETVEKLHRNYESLLHRYLYSIHKEEAEQRF
ASIPKALVALRKVAENAVTLFLGAGNTTEAASLPKEFFATNY
Ligand information
>3gyt Chain B (length=10) Species:
9606
(Homo sapiens) [
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KSLLQQLLTE
Receptor-Ligand Complex Structure
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PDB
3gyt
Identification of the nuclear receptor DAF-12 as a therapeutic target in parasitic nematodes.
Resolution
2.4 Å
Binding residue
(original residue number in PDB)
K571 F585 K589 S743 E747
Binding residue
(residue number reindexed from 1)
K60 F74 K78 S232 E236
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:3gyt
,
PDBe:3gyt
,
PDBj:3gyt
PDBsum
3gyt
PubMed
19497877
UniProt
Q9XZJ5
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