Structure of PDB 3gme Chain A Binding Site BS01

Receptor Information
>3gme Chain A (length=482) Species: 331111 (Escherichia coli O139:H28 str. E24377A) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MLNPIVRKFQYGQHTVTLETGMMARQATAAVMVSMDDTAVFVTVVGQKKA
KPGQDFFPLTVNYQERTYAAGRIPGSFRPSEGETLIARLIDRPIRPLFPE
GFVNEVQVIATVVSVNPQVNPDIVAMIGASAALSLSGIPFNGPIGAARVG
YINDQYVLNPTQDELKESKLDLVVAGTEAAVLMVESEAELLSEDQMLGAV
VFGHEQQQVVIQNINELVKEAGKPRWDWQPEPVNEALNARVTDKQERYLH
AIEKNVVRSRVLAGEPRIDGREKDMIRGLDVRTGVLPRTHGSALFTRGET
QALVTATLGTDTFLFHYNFPPYSVGETGMVGSPKRREIGHGRLAKRGVLA
VMPDMDKFPYTVRVVSEITESNGSSSMASVCGASLALMDAGVPIKAAVAG
IAMGLVKEGDNYVVLSDILGDEDHLGDMDFKVAGSRDGISALQMDIKIEG
ITKEIMQVALNQAKGARLHILGVMEQAINAPR
Ligand information
>3gme Chain D (length=21) Species: 562 (Escherichia coli) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
GAAGGHTATHHASAAPARPQP
Receptor-Ligand Complex Structure
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PDB3gme Crystal structure of Escherichia coli polynucleotide phosphorylase core bound to RNase E, RNA and manganese: implications for catalytic mechanism and RNA degradosome assembly.
Resolution2.4 Å
Binding residue
(original residue number in PDB)		E320 D322 I324 G326 L327 D328 V329 R330 T331 G332 V333 P335 G528 V536 A540
Binding residue
(residue number reindexed from 1)		E272 D274 I276 G278 L279 D280 V281 R282 T283 G284 V285 P287 G465 V473 A477
Enzymatic activity
Enzyme Commision number 2.7.7.8: polyribonucleotide nucleotidyltransferase.
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0004654 polyribonucleotide nucleotidyltransferase activity
Biological Process
GO:0006396 RNA processing
GO:0006402 mRNA catabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:3gme, PDBe:3gme, PDBj:3gme
PDBsum3gme
PubMed19327365
UniProtA7ZS61|PNP_ECO24 Polyribonucleotide nucleotidyltransferase (Gene Name=pnp)

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