Structure of PDB 3g73 Chain A Binding Site BS01

Receptor Information
>3g73 Chain A (length=90) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SVSERPPYSYMAMIQFAINSTERKRMTLKDIYTWIEDHFPYFKHIAKPGW
KNSIRHNLSLHDMFVRETSANGKVSFWTIHPSANRYLTLD
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3g73 Structure of the FoxM1 DNA-recognition domain bound to a promoter sequence
Resolution2.21 Å
Binding residue
(original residue number in PDB)		R236 S240 Y241 K278 N283 S284 H287
Binding residue
(residue number reindexed from 1)		R5 S9 Y10 K47 N52 S53 H56
Binding affinityPDBbind-CN: Kd=7uM
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0000086 G2/M transition of mitotic cell cycle
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:3g73, PDBe:3g73, PDBj:3g73
PDBsum3g73
PubMed20360045
UniProtQ08050|FOXM1_HUMAN Forkhead box protein M1 (Gene Name=FOXM1)

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