Structure of PDB 3g6p Chain A Binding Site BS01
Receptor Information
>3g6p Chain A (length=74) Species:
10116
(Rattus norvegicus) [
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SHMCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRNDCIIDK
IRRKNCPACRYRKCLQAGMNLEAR
Ligand information
>3g6p Chain C (length=18) [
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ccagaacaccctgttctg
Receptor-Ligand Complex Structure
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PDB
3g6p
DNA binding site sequence directs glucocorticoid receptor structure and activity.
Resolution
1.985 Å
Binding residue
(original residue number in PDB)
C450 H451 Y452 K461 K465 R510
Binding residue
(residue number reindexed from 1)
C14 H15 Y16 K25 K29 R74
Binding affinity
PDBbind-CN
: Kd=0.44uM
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0003700
DNA-binding transcription factor activity
GO:0008270
zinc ion binding
GO:0043565
sequence-specific DNA binding
Biological Process
GO:0006355
regulation of DNA-templated transcription
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Molecular Function
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Biological Process
External links
PDB
RCSB:3g6p
,
PDBe:3g6p
,
PDBj:3g6p
PDBsum
3g6p
PubMed
19372434
UniProt
P06536
|GCR_RAT Glucocorticoid receptor (Gene Name=Nr3c1)
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