Structure of PDB 3g3t Chain A Binding Site BS01

Receptor Information
>3g3t Chain A (length=274) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FVRQTTKYWVHPDNITELKLIILKHLPVLEREDSAITSIYFDNENLDLYY
GRLRKDEGAEAHRLRWYGGMSTDTIFVERKTHREDWTGEKSVKARFALKE
RHVNDFLKGKYTVDQVFAKMRKEGKKPMNEIENLEALASEIQYVMLKKKL
RPVVRSFYNRTAFQLPGDARVRISLDTELTMVREDNFDGVDRTHKNWRRT
DIGVDWPFKQLDDKDICRFPYAVLEVKLQTQLGQEPPEWVRELVGSHLVE
PVPKFSKFIHGVATLLNDKVDSIP
Ligand information
Ligand IDPO4
InChIInChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)/p-3
InChIKeyNBIIXXVUZAFLBC-UHFFFAOYSA-K
SMILES
SoftwareSMILES
CACTVS 3.341[O-][P]([O-])([O-])=O
ACDLabs 10.04[O-]P([O-])([O-])=O
OpenEye OEToolkits 1.5.0[O-]P(=O)([O-])[O-]
FormulaO4 P
NamePHOSPHATE ION
ChEMBL
DrugBankDB14523
ZINC
PDB chain3g3t Chain A Residue 1000 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB3g3t Catalytic core of a membrane-associated eukaryotic polyphosphate polymerase.
Resolution1.85 Å
Binding residue
(original residue number in PDB)		Y241 K281 S457 K458 F459
Binding residue
(residue number reindexed from 1)		Y40 K80 S256 K257 F258
Annotation score1
Enzymatic activity
Enzyme Commision number 2.7.4.1: ATP-polyphosphate phosphotransferase.
External links
PDB RCSB:3g3t, PDBe:3g3t, PDBj:3g3t
PDBsum3g3t
PubMed19390046
UniProtP47075|VTC4_YEAST Vacuolar transporter chaperone complex subunit 4 (Gene Name=VTC4)

[Back to BioLiP]