Structure of PDB 3g0h Chain A Binding Site BS01

Receptor Information
>3g0h Chain A (length=408) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SLLNKLIRSNLVDNTNQVEVLQRDPNSPLYSVKSFEELRLKPQLLQGVYA
MGFNRPSKIQENALPLMLAEPPQNLIAQSQSGTGKTAAFVLAMLSQVEPA
NKYPQCLCLSPTYELALQTGKVIEQMGKFYPELKLAYAVRGNKLERGQKI
SEQIVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEADVMIATQGHQDQSIR
IQRMLPRNCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKREEETLDTIKQ
YYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTRKTASWLAAELSKEGHQ
VALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFD
LPVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMVDSKHSMNILNRIQEHF
NKKIERLD
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB3g0h The DEXD/H-box RNA Helicase DDX19 Is Regulated by an {alpha}-Helical Switch.
Resolution2.7 Å
Binding residue
(original residue number in PDB)		P170 T171 R199 K202 L203 T217 G219 T220 D223 K227 L228 F230 H253 Q256 H341 T342 R343 S364 G365 R372 T390 N391 V392
Binding residue
(residue number reindexed from 1)		P111 T112 R140 K143 L144 T158 G160 T161 D164 K168 L169 F171 H194 Q197 H282 T283 R284 S305 G306 R313 T331 N332 V333
Enzymatic activity
Enzyme Commision number 3.6.4.13: RNA helicase.
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003724 RNA helicase activity
GO:0005524 ATP binding

View graph for
Molecular Function
External links
PDB RCSB:3g0h, PDBe:3g0h, PDBj:3g0h
PDBsum3g0h
PubMed19244245
UniProtQ9UMR2|DD19B_HUMAN ATP-dependent RNA helicase DDX19B (Gene Name=DDX19B)

[Back to BioLiP]