Structure of PDB 3ft3 Chain A Binding Site BS01
Receptor Information
>3ft3 Chain A (length=275) Species:
9606
(Homo sapiens) [
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GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAP
WIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYG
CDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAA
HVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEAT
LRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWVAVVVP
SGQEQRYTCHVQHEGLPKPLTLRWE
Ligand information
>3ft3 Chain P (length=9) Species:
9606
(Homo sapiens) [
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VLHDDLLEA
Receptor-Ligand Complex Structure
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PDB
3ft3
Steric hindrance and fast dissociation explain the lack of immunogenicity of the minor histocompatibility HA-1Arg Null allele.
Resolution
1.95 Å
Binding residue
(original residue number in PDB)
Y7 E63 K66 V67 H70 V76 D77 R97 Y99 T143 K146 W147 L156 Y159 W167 Y171
Binding residue
(residue number reindexed from 1)
Y7 E63 K66 V67 H70 V76 D77 R97 Y99 T143 K146 W147 L156 Y159 W167 Y171
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:3ft3
,
PDBe:3ft3
,
PDBj:3ft3
PDBsum
3ft3
PubMed
19342659
UniProt
P04439
|HLAA_HUMAN HLA class I histocompatibility antigen, A alpha chain (Gene Name=HLA-A)
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