Structure of PDB 3ft2 Chain A Binding Site BS01
Receptor Information
>3ft2 Chain A (length=275) Species:
9606
(Homo sapiens) [
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GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAP
WIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYG
CDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAA
HVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEAT
LRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWVAVVVP
SGQEQRYTCHVQHEGLPKPLTLRWE
Ligand information
>3ft2 Chain P (length=9) [
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VLRDDLLEA
Receptor-Ligand Complex Structure
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PDB
3ft2
Steric hindrance and fast dissociation explain the lack of immunogenicity of the minor histocompatibility HA-1Arg Null allele.
Resolution
1.8 Å
Binding residue
(original residue number in PDB)
Y7 F9 E63 K66 V67 H70 V76 D77 Y84 R97 Y99 H114 T143 K146 W147 L156 Y159 L160 W167 Y171
Binding residue
(residue number reindexed from 1)
Y7 F9 E63 K66 V67 H70 V76 D77 Y84 R97 Y99 H114 T143 K146 W147 L156 Y159 L160 W167 Y171
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:3ft2
,
PDBe:3ft2
,
PDBj:3ft2
PDBsum
3ft2
PubMed
19342659
UniProt
P04439
|HLAA_HUMAN HLA class I histocompatibility antigen, A alpha chain (Gene Name=HLA-A)
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