Structure of PDB 3fs1 Chain A Binding Site BS01
Receptor Information
>3fs1 Chain A (length=230) Species:
9606
(Homo sapiens) [
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SLPSINALLQAEVLSRQITSPVSGINGDIRAKKIASIADVCESMKEQLLV
LVEWAKYIPAFCELPLDDQVALLRAHAGEHLLLGATKRSMVFKDVLLLGN
DYIVPRHCPELAEMSRVSIRILDELVLPFQELQIDDNEYAYLKAIIFFDP
DAKGLSDPGKIKRLRSQVQVSLEDYINDRQYDSRGRFGELLLLLPTLQSI
TWQMIEQIQFIKLFGMAKIDNLLQEMLLGG
Ligand information
>3fs1 Chain B (length=9) Species:
9606
(Homo sapiens) [
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AALAALLAA
Receptor-Ligand Complex Structure
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PDB
3fs1
Multiple binding modes between HNF4alpha and the LXXLL motifs of PGC-1alpha lead to full activation
Resolution
2.2 Å
Binding residue
(original residue number in PDB)
K194 R212 E363
Binding residue
(residue number reindexed from 1)
K56 R74 E225
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:3fs1
,
PDBe:3fs1
,
PDBj:3fs1
PDBsum
3fs1
PubMed
19846556
UniProt
P41235
|HNF4A_HUMAN Hepatocyte nuclear factor 4-alpha (Gene Name=HNF4A)
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