Structure of PDB 3fm9 Chain A Binding Site BS01

Receptor Information

>3fm9 Chain A (length=220) Species: 1360 (Lactococcus lactis subsp. lactis)

MFKAVLFDLDGVITDPAEYHFRAWKALAEEIGINGVDRQFNEQLKGVSRE
DSLQKILDLADKKVSAEEFKELAKRKNDNYVKMIQDVSPADVYPGILQLL
KDLRSNKIKIALASASKNGPFLLERMNLTGYFDAIADPAEVAASKPAPDI
FIAAAHAVGVAPSESIGLEDSQAGIQAIKDSGALPIGVGRPEDLGDDIVI
VPDTSHYTLEFLKEVWLQKQ

Ligand information

• Ligand ID: MG
• InChI: InChI=1S/Mg/q+2
• InChIKey: JLVVSXFLKOJNIY-UHFFFAOYSA-N
• SMILES:
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Mg+2]
  CACTVS 3.341: [Mg++]
• Formula: Mg
• Name: MAGNESIUM ION
• DrugBank: DB01378
• PDB chain: 3fm9 Chain A Residue 222

Receptor-Ligand Complex Structure

Structure summary

• PDB: 3fm9 Analysis of the structural determinants underlying discrimination between substrate and solvent in beta-phosphoglucomutase catalysis.
• Resolution: 2.7 Å
• Binding residue (original residue number in PDB): D8 D10 E169 D170
• Binding residue (residue number reindexed from 1): D8 D10 E169 D170
• Annotation score: 1

Enzymatic activity

• Catalytic site (original residue number in PDB): D8 L9 D10 P16 K45 S114 A115 K145 E169 D170
• Catalytic site (residue number reindexed from 1): D8 L9 D10 P16 K45 S114 A115 K145 E169 D170
• Enzyme Commision number: 5.4.2.6: beta-phosphoglucomutase.

Gene Ontology

Molecular Function

• GO:0000287 magnesium ion binding
• GO:0008801 beta-phosphoglucomutase activity
• GO:0016853 isomerase activity
• GO:0046872 metal ion binding

Biological Process

• GO:0005975 carbohydrate metabolic process

Cellular Component

• GO:0005737 cytoplasm

External links

• PDB: RCSB:3fm9, PDBe:3fm9, PDBj:3fm9
• PDBsum: 3fm9
• PubMed: 19154134
• UniProt: P71447|PGMB_LACLA Beta-phosphoglucomutase (Gene Name=pgmB)