Structure of PDB 3fiv Chain A Binding Site BS01

Receptor Information
>3fiv Chain A (length=111) Species: 11673 (Feline immunodeficiency virus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TTTTLEKRPEILIFVNGYPIKFLLNTGADITILNRRDFQVKNSIENGRQN
MIGVGGGKRGTNYINVHLEIRDENYKTQCIFGNVCVLEDNSLIQPLLGRD
NMIKFNIRLVM
Ligand information
Receptor-Ligand Complex Structure
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PDB3fiv Crystal structures of the inactive D30N mutant of feline immunodeficiency virus protease complexed with a substrate and an inhibitor.
Resolution1.85 Å
Binding residue
(original residue number in PDB)		R13 L28 G32 A33 D34 M56 I57 G58 I98
Binding residue
(residue number reindexed from 1)		R8 L23 G27 A28 D29 M51 I52 G53 I93
Enzymatic activity
Enzyme Commision number 2.7.7.-
2.7.7.49: RNA-directed DNA polymerase.
3.1.-.-
3.1.13.2: exoribonuclease H.
3.1.26.13: retroviral ribonuclease H.
3.4.23.-
3.6.1.23: dUTP diphosphatase.
Gene Ontology
Molecular Function
GO:0004190 aspartic-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:3fiv, PDBe:3fiv, PDBj:3fiv
PDBsum3fiv
PubMed9271500
UniProtP16088|POL_FIVPE Pol polyprotein (Gene Name=pol)

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