Structure of PDB 3fe7 Chain A Binding Site BS01

Receptor Information
>3fe7 Chain A (length=83) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QVRPKLPLLKILHAAGAQGEMFTVKEVMHYLGQYIMVKQLYDQQEQHMVY
CGGDLLGELLGRQSFSVKDPSPLYDMLRKNLVT
Ligand information
Receptor-Ligand Complex Structure
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PDB3fe7 Crystal Structures of Human MdmX (HdmX) in Complex with p53 Peptide Analogues Reveal Surprising Conformational Changes
Resolution1.35 Å
Binding residue
(original residue number in PDB)		M53 G57 I60 M61 Y66 Q71 H72 V92
Binding residue
(residue number reindexed from 1)		M28 G32 I35 M36 Y41 Q46 H47 V67
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0043066 negative regulation of apoptotic process
GO:0051726 regulation of cell cycle
Cellular Component
GO:0005634 nucleus

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Biological Process
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Cellular Component
External links
PDB RCSB:3fe7, PDBe:3fe7, PDBj:3fe7
PDBsum3fe7
PubMed19153082
UniProtO15151|MDM4_HUMAN Protein Mdm4 (Gene Name=MDM4)

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