Structure of PDB 3fdo Chain A Binding Site BS01

Receptor Information
>3fdo Chain A (length=90) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
IQINQVRPKLPLLKILHAAGAQGEMFTVKEVMHYLGQYIMVKQLYDQQEQ
HMVYCGGDLLGELLGRQSFSVKDPSPLYDMLRKNLVTLAT
Ligand information
Receptor-Ligand Complex Structure
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PDB3fdo High affinity interaction of the p53 peptide-analogue with human Mdm2 and Mdmx.
Resolution1.4 Å
Binding residue
(original residue number in PDB)		M53 L56 G57 I60 Y66 Q71 H72 V92 L98
Binding residue
(residue number reindexed from 1)		M32 L35 G36 I39 Y45 Q50 H51 V71 L77
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0043066 negative regulation of apoptotic process
GO:0051726 regulation of cell cycle
Cellular Component
GO:0005634 nucleus

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Biological Process
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Cellular Component
External links
PDB RCSB:3fdo, PDBe:3fdo, PDBj:3fdo
PDBsum3fdo
PubMed19305137
UniProtO15151|MDM4_HUMAN Protein Mdm4 (Gene Name=MDM4)

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