Structure of PDB 3f2o Chain A Binding Site BS01

Receptor Information
>3f2o Chain A (length=203) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
YCKPTRLDLLLDMPPVSYDVQLLHSWNNNDRSLNVFVKEDDKLIFHRHPV
AQSTDAIRGKVGYTRGLHVWQITWAMRQRGTHAVVGVATADAPLHSVGYT
TLVGNNHESWGWDLGRNRLYHDGKNQPSKTYPAFLEPDETFIVPDSFLVA
LDMDDGTLSFIVDGQYMGVAFRGLKGKKLYPVVSAVWGHCEIRMRYLNGL
DPE
Ligand information
>3f2o Chain C (length=18) Species: 7227 (Drosophila melanogaster) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
DINNNNNIVEDVERKREF
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3f2o Structural basis for Par-4 recognition by the SPRY domain- and SOCS box-containing proteins SPSB1, SPSB2, and SPSB4.
Resolution2.05 Å
Binding residue
(original residue number in PDB)		S62 L63 N64 R77 P79 V80 A81 G110 T111 H125 V127 Y129 V216 W217 G218
Binding residue
(residue number reindexed from 1)		S32 L33 N34 R47 P49 V50 A51 G80 T81 H95 V97 Y99 V186 W187 G188
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:3f2o, PDBe:3f2o, PDBj:3f2o
PDBsum3f2o
PubMed20561531
UniProtQ96BD6|SPSB1_HUMAN SPRY domain-containing SOCS box protein 1 (Gene Name=SPSB1)

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