Structure of PDB 3f2d Chain A Binding Site BS01

Receptor Information
>3f2d Chain A (length=993) Species: 1462 (Geobacillus kaustophilus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VRRLETIVEEERRVVVQGYVFDAEVSELKSGRTLLTMKITDYTNSILVKM
FSRDKEDAELMSGVKKGMWVKVRGSVQNDTFVRDLVIIANDLNEIAANER
QDTAPEGEKRVELHLHTPMSQMDAVTSVTKLIEQAKKWGHPAIAVTDHAV
VQSFPEAYSAAKKHGMKVIYGLEANIVDDPFHVTLLAQNETGLKNLFKLV
SLSHIQYFHRVPRIPRSVLVKHRDGLLVGSGCDKGELFDNVEDIARFYDF
LEVHPPDVYKPLVKDEEMIKNIIRSIVALGEKLDIPVVATGNVHYLNPED
KIYRKILIHSQGGANPLNRHELPDVYFRTTNEMLDCFSFLGPEKAKEIVV
DNTQKIASLIGDVKPIKDELYTPRIEGADEEIREMSYRRAKEIYGDPLPK
LVEERLEKELKSIIGHGFAVIYLISHKLVKKSLDDGYLVGSRGSVGSSFV
ATMTEITEVNPLPPHYVCPNCKHSEFFNDGSVGSGFDLPDKNCPRCGTKY
KKDGHDIPFETFLGFKGDKVPDIDLNFSGEYQPRAHNYTKVLFGEDNVYR
AGTIGTVADKTAYGFVKAYASDHNLELRGAEIDRLAAGCTGVKRTTGQHP
GGIIVVPDYMEIYDFTPIQYPADDTSSEWRTTHFDFHSIHDNLLKLDILG
HDDPTVIRMLQDLSGIDPKTIPTDDPDVMGIFSSTEPLGVTPEQIMCNVG
TIGIPEFGTRFVRQMLEETRPKTFSELVQISGLSHGTDVWLGNAQELIQN
GTCTLSEVIGCRDDIMVYLIYRGLEPSLAFKIMESVRKGKGLTPEFEAEM
RKHDVPEWYIDSCKKIKYMFPKAHAAAYVLMAVRIAYFKVHHPLLYYASY
FTVRAEDFDLDAMIKGSAAIRKRIEEINAKGIQATAKEKSLLTVLEVALE
MCERGFSFKNIDLYRSQATEFVIDGNSLIPPFNAIPGLGTNVAQAIVRAR
EEGEFLSKEDLQQRGKLSKTLLEYLESRGCLDSLPDHNQLSLF
Ligand information
Receptor-Ligand Complex Structure
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PDB3f2d Structure of PolC reveals unique DNA binding and fidelity determinants.
Resolution2.51 Å
Binding residue
(original residue number in PDB)
R893 I1005 T1007 A1009 T1012 H1050 D1098 K1338 G1388 G1390
Binding residue
(residue number reindexed from 1)
R442 I554 T556 A558 T561 H599 D647 K887 G937 G939
Enzymatic activity
Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003824 catalytic activity
GO:0003887 DNA-directed DNA polymerase activity
GO:0008408 3'-5' exonuclease activity
Biological Process
GO:0006260 DNA replication
Cellular Component
GO:0005737 cytoplasm

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:3f2d, PDBe:3f2d, PDBj:3f2d
PDBsum3f2d
PubMed19106298
UniProtQ5L0J3

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