Structure of PDB 3f22 Chain A Binding Site BS01

Receptor Information
>3f22 Chain A (length=65) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SIYQDQEQRILKFLEELGEGKATTAHDLSGKLGTPKKEINRVLYSLAKKG
KLQKEAGTPPLWKIA
Ligand information
Receptor-Ligand Complex Structure
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PDB3f22 The structures of non-CG-repeat Z-DNAs co-crystallized with the Z-DNA-binding domain, hZ{alpha}ADAR1
Resolution2.5 Å
Binding residue
(original residue number in PDB)		K170 N173 R174 Y177 T191 P192 P193
Binding residue
(residue number reindexed from 1)		K37 N40 R41 Y44 T58 P59 P60
Enzymatic activity
Enzyme Commision number 3.5.4.37: double-stranded RNA adenine deaminase.
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003726 double-stranded RNA adenosine deaminase activity

View graph for
Molecular Function
External links
PDB RCSB:3f22, PDBe:3f22, PDBj:3f22
PDBsum3f22
PubMed19074195
UniProtP55265|DSRAD_HUMAN Double-stranded RNA-specific adenosine deaminase (Gene Name=ADAR)

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