Structure of PDB 3f21 Chain A Binding Site BS01

Receptor Information
>3f21 Chain A (length=67) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LSIYQDQEQRILKFLEELGEGKATTAHDLSGKLGTPKKEINRVLYSLAKK
GKLQKEAGTPPLWKIAV
Ligand information
Receptor-Ligand Complex Structure
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PDB3f21 The structures of non-CG-repeat Z-DNAs co-crystallized with the Z-DNA-binding domain, hZ{alpha}ADAR1
Resolution2.2 Å
Binding residue
(original residue number in PDB)		K169 K170 N173 R174 Y177 T191 P192 P193
Binding residue
(residue number reindexed from 1)		K37 K38 N41 R42 Y45 T59 P60 P61
Enzymatic activity
Enzyme Commision number 3.5.4.37: double-stranded RNA adenine deaminase.
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003726 double-stranded RNA adenosine deaminase activity

View graph for
Molecular Function
External links
PDB RCSB:3f21, PDBe:3f21, PDBj:3f21
PDBsum3f21
PubMed19074195
UniProtP55265|DSRAD_HUMAN Double-stranded RNA-specific adenosine deaminase (Gene Name=ADAR)

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