Structure of PDB 3eu7 Chain A Binding Site BS01
Receptor Information
>3eu7 Chain A (length=313) Species:
9606
(Homo sapiens) [
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NLQLVSELKNPSGSCSVDVSAMFWEGCKEPCIITACEDVVSLWKALDAWQ
WEKLYTWHFAEVPVLQIVPVPDVYNLVCVALGNLEIREIRALFCSEKQVL
LKSGNIKAVLGLTKRRLVSSSGTLSDQQVEVMTFAGGGKENQFLMPPEET
ILTFAEVQGMQEALLGTTIMNNIVIWNLKTGQLLKKMHIDDSYQASVCHK
AYSEMGLLFIVLSHPVFQLIVINPKTTLSVGVMLYCLPPGQAGRFLEGDV
KDHCAAAILTSGTIAIWDLLLGQCTALLPPVSDQHWSFVKWSGTDSHLLA
GQKDGNIFVYHYS
Ligand information
>3eu7 Chain X (length=14) Species:
9606
(Homo sapiens) [
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LGPISLNWFEELSS
Receptor-Ligand Complex Structure
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PDB
3eu7
Structural basis for recruitment of BRCA2 by PALB2
Resolution
2.2 Å
Binding residue
(original residue number in PDB)
M1022 E1024 A1025 N1039 L1046 M1067 N1096 P1097 K1098 T1099
Binding residue
(residue number reindexed from 1)
M160 E162 A163 N177 L184 M205 N223 P224 K225 T226
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0003677
DNA binding
Biological Process
GO:0000724
double-strand break repair via homologous recombination
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Molecular Function
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Biological Process
External links
PDB
RCSB:3eu7
,
PDBe:3eu7
,
PDBj:3eu7
PDBsum
3eu7
PubMed
19609323
UniProt
Q86YC2
|PALB2_HUMAN Partner and localizer of BRCA2 (Gene Name=PALB2)
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