Structure of PDB 3erd Chain A Binding Site BS01
Receptor Information
>3erd Chain A (length=245) Species:
9606
(Homo sapiens) [
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SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL
VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLF
APNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILL
NSGVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRL
AQLLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLLLEMLDAHRL
Ligand information
>3erd Chain C (length=11) Species:
9606
(Homo sapiens) [
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HKILHRLLQDS
Receptor-Ligand Complex Structure
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PDB
3erd
The structural basis of estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifen.
Resolution
2.03 Å
Binding residue
(original residue number in PDB)
I358 K362 L372 V376 E380 D538 E542 M543
Binding residue
(residue number reindexed from 1)
I54 K58 L68 V72 E76 D234 E238 M239
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:3erd
,
PDBe:3erd
,
PDBj:3erd
PDBsum
3erd
PubMed
9875847
UniProt
P03372
|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)
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