Structure of PDB 3er8 Chain A Binding Site BS01

Receptor Information
>3er8 Chain A (length=288) Species: 10254 (Vaccinia virus WR) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MDVVSLDKPFMYFEEIDNELDYEPESKLPYQGQLKLLLGELFFLSKLQRH
GILDGATVVYIGSAPGTHIRYLRDHFYNLGVIIKWMLIDGRHHDPILNGL
RDVTLVTRFVDEEYLRSIKKQLHPSKIILISDVASGNEPSTADLLSNYAL
QNVMISILNPVASSLKWRCPFPDQWIKDFYIPHGNKMLQPFAPSYSAEMR
LLSIYTGENMRLTRVTKSDAVNYEKKMYYLNKIVRNKVVVNFDYPNQEYD
YFHMYFMLRTVYCNKTFPTTKAKVLFLQQSIFRFLNIP
Ligand information
Receptor-Ligand Complex Structure
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PDB3er8 Polymerase Translocation with Respect to Single-Stranded Nucleic Acid: Looping or Wrapping of Primer around a Poly(A) Polymerase
Resolution3.18 Å
Binding residue
(original residue number in PDB)		L106 R107
Binding residue
(residue number reindexed from 1)		L100 R101
Enzymatic activity
Enzyme Commision number 2.1.1.57: methyltransferase cap1.
Gene Ontology
Molecular Function
GO:0003746 translation elongation factor activity
GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity
Biological Process
GO:0006370 7-methylguanosine mRNA capping
GO:0031440 regulation of mRNA 3'-end processing

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Molecular Function
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Biological Process
External links
PDB RCSB:3er8, PDBe:3er8, PDBj:3er8
PDBsum3er8
PubMed19446524
UniProtP07617|MCE_VACCW Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase (Gene Name=OPG102)

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