Structure of PDB 3eh1 Chain A Binding Site BS01

Receptor Information
>3eh1 Chain A (length=737) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QPESLRPVNLTQERNILPMTPVWAPVPNLNADLKKLNCSPDSFRCTLTNI
PQTQALLNKAKLPLGLLLHPFRDLTQLPVITSNTIVRCRSCRTYINPFVS
FIDQRRWKCNLCYRVNDVPEEFMEPHKRPEVQNSTVEFIASSDYMLRPPQ
PAVYLFVLDVSHNAVEAGYLTILCQSLLENLDKLPGDSRTRIGFMTFDST
IHFYNLQEGLSQPQMLIVSDIDDVFLPTPDSLLVNLYESKELIKDLLNAL
PNMFTNTRETHSALGPALQAAFKLMSPTGGRVSVFQTQLPSLGAGLLQSR
EDPNQRSSTKVVQHLGPATDFYKKLALDCSGQQTAVDLFLLSSQYSDLAS
LACMSKYSAGCIYYYPSFHYTHNPSQAEKLQKDLKRYLTRKIGFEAVMRI
RCTKGLSMHTFHGNFFVRSTDLLSLANINPDAGFAVQLSIEESLTDTSLV
CFQTALLYTSSKGERRIRVHTLCLPVVSSLADVYAGVDVQAAICLLANMA
VDRSVSSSLSDARDALVNAVVDSLSAYGSTVSALMAPSSLKLFPLYVLAL
LKQKAFRTGTSTRLDDRVYAMCQIKSQPLVHLMKMIHPNLYRIDRLTDEG
AVHVNDRIVPQPPLQKLSAEKLTREGAFLMDCGSVFYIWVGKGCDNNFIE
DVLGYTNFASIPQKMTHLPELDTLSSERARSFITWLRDSRPLSPILHIVK
DESPAKAEFFQHLIEDRTEAAFSYYEFLLHVQQQICK
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain3eh1 Chain A Residue 1269 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3eh1 Structural basis of cargo membrane protein discrimination by the human COPII coat machinery.
Resolution1.8 Å
Binding residue
(original residue number in PDB)		C605 C608 C626 C629
Binding residue
(residue number reindexed from 1)		C88 C91 C109 C112
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding
Biological Process
GO:0006886 intracellular protein transport
GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport
Cellular Component
GO:0030127 COPII vesicle coat

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3eh1, PDBe:3eh1, PDBj:3eh1
PDBsum3eh1
PubMed18843296
UniProtO95487|SC24B_HUMAN Protein transport protein Sec24B (Gene Name=SEC24B)

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