Structure of PDB 3eb6 Chain A Binding Site BS01

Receptor Information
>3eb6 Chain A (length=64) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DLPVEEQLRRLQEERTCKVCMDKEVSIVFIPCGHLVVCKDCAPSLRKCPI
CRSTIKGTVRTFLS
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain3eb6 Chain A Residue 1001 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3eb6 Structures of the cIAP2 RING Domain Reveal Conformational Changes Associated with Ubiquitin-conjugating Enzyme (E2) Recruitment.
Resolution3.4 Å
Binding residue
(original residue number in PDB)		C557 C560 C578 C581
Binding residue
(residue number reindexed from 1)		C17 C20 C38 C41
Annotation score4
Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
External links
PDB RCSB:3eb6, PDBe:3eb6, PDBj:3eb6
PDBsum3eb6
PubMed18784070
UniProtQ13489|BIRC3_HUMAN Baculoviral IAP repeat-containing protein 3 (Gene Name=BIRC3)

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