Structure of PDB 3e45 Chain A Binding Site BS01

Receptor Information
>3e45 Chain A (length=246) Species: 727 (Haemophilus influenzae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SFIKPIYQDINSILIGQKVKRGEPFEKLVYKFLKENLSDLTFKQYEYLND
LFMKNPAIIGHEARYKLFNSPTLLFLLSRGKAATENWSIENLFEEKQNDT
ADILLVKDQFYELLDVKTRNISKSAFAPNIISAYKLAQTCAKMIDNKEFD
LFDINYLEVDWELNGEDLVCVSTSFAELFKSEPSELYINWAAAMQIQFHV
RDLDQGFNGTREEWAKSYLKHFVTQAEQRAISMIDKFVKPFKKYIL
Ligand information
Receptor-Ligand Complex Structure
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PDB3e45 DNA distortion and specificity in a sequence-specific endonuclease.
Resolution2.78 Å
Binding residue
(original residue number in PDB)		G92 K93 K108 Q109 F138 Y199 N201 A204 R241
Binding residue
(residue number reindexed from 1)		G80 K81 K96 Q97 F126 Y187 N189 A192 R229
Enzymatic activity
Enzyme Commision number 3.1.21.4: type II site-specific deoxyribonuclease.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004519 endonuclease activity
GO:0009036 type II site-specific deoxyribonuclease activity
Biological Process
GO:0009307 DNA restriction-modification system

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Molecular Function
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Biological Process
External links
PDB RCSB:3e45, PDBe:3e45, PDBj:3e45
PDBsum3e45
PubMed18762194
UniProtP17743|T2C2_HAEIF Type II restriction enzyme HincII (Gene Name=hincIIR)

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