Structure of PDB 3e42 Chain A Binding Site BS01

Receptor Information

>3e42 Chain A (length=248) Species: 727 (Haemophilus influenzae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

SFIKPIYQDINSILIGQKVKRPAAGEPFEKLVYKFLKENLSDLTFKQYEY
LNDLFMKNPAIIGHEARYKLFNSPTLLFLLSRGKAATENWSIENLFEEKQ
NDTADILLVKDQFYELLDVKTRNISKSAFAPNIISAYKLAQTCAKMIDNK
EFDLFDINYLEVDWELNGEDLVCVSTSFAELFKSEPSELYINWAAAMQIQ
FHVRDLDQGFNGTREEWAKSYLKHFVTQAEQRAISMIDKFVKPFKKYI

Ligand information

>3e42 Chain E (length=14) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

gccggtcgaccggc

Receptor-Ligand Complex Structure

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Structure summary

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PDB	3e42 DNA distortion and specificity in a sequence-specific endonuclease.
Resolution	2.68 Å
Binding residue (original residue number in PDB)	G92 K93 K108 F138 Y199 N201 A203 A204 R241
Binding residue (residue number reindexed from 1)	G83 K84 K99 F129 Y190 N192 A194 A195 R232

Enzymatic activity

Enzyme Commision number

3.1.21.4: type II site-specific deoxyribonuclease.

Gene Ontology

	Molecular Function
GO:0003677	DNA binding
GO:0004519	endonuclease activity
GO:0009036	type II site-specific deoxyribonuclease activity

	Biological Process
GO:0009307	DNA restriction-modification system

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Biological Process

External links

PDB	RCSB:3e42, PDBe:3e42, PDBj:3e42
PDBsum	3e42
PubMed	18762194
UniProt	P17743\|T2C2_HAEIF Type II restriction enzyme HincII (Gene Name=hincIIR)

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