Structure of PDB 3e40 Chain A Binding Site BS01

Receptor Information
>3e40 Chain A (length=247) Species: 727 (Haemophilus influenzae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SFIKPIYQDINSILIGQKVKRAGEPFEKLVYKFLKENLSDLTFKQYEYLN
DLFMKNPAIIGHEARYKLFNSPTLLFLLSRGKAATENWSIENLFEEKQND
TADILLVKDQFYELLDVKTRNISKSAFAPNIISAYKLAQTCAKMIDNKEF
DLFDINYLEVDWELNGEDLVCVSTSFAELFKSEPSELYINWAAAMQIQFH
VRDLDQGFNGTREEWAKSYLKHFVTQAEQRAISMIDKFVKPFKKYIL
Ligand information
Receptor-Ligand Complex Structure
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PDB3e40 DNA distortion and specificity in a sequence-specific endonuclease.
Resolution2.1 Å
Binding residue
(original residue number in PDB)		G92 K93 K108 Q109 F138 Y199 N201 A203 A204 R241
Binding residue
(residue number reindexed from 1)		G81 K82 K97 Q98 F127 Y188 N190 A192 A193 R230
Enzymatic activity
Enzyme Commision number 3.1.21.4: type II site-specific deoxyribonuclease.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004519 endonuclease activity
GO:0009036 type II site-specific deoxyribonuclease activity
Biological Process
GO:0009307 DNA restriction-modification system

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Molecular Function
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Biological Process
External links
PDB RCSB:3e40, PDBe:3e40, PDBj:3e40
PDBsum3e40
PubMed18762194
UniProtP17743|T2C2_HAEIF Type II restriction enzyme HincII (Gene Name=hincIIR)

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