Structure of PDB 3e3y Chain A Binding Site BS01

Receptor Information

>3e3y Chain A (length=242) Species: 727 (Haemophilus influenzae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

SFIKPIYQDINSILIGQKVKRFEKLVYKFLKENLSDLTFKQYEYLNDLFM
KNPAIIGHEARYKLFNSPTLLFLLSRGKAATENWSIENLFEEKNDTADIL
LVKDQFYELLDVKTRNISKSAFAPNIISAYKLAQTCAKMIDNKEFDLFDI
NYLEVDWELNGEDLVCVSTSFAELFKSEPSELYINWAAAMQIQFHVRDLD
QGFNGTREEWAKSYLKHFVTQAEQRAISMIDKFVKPFKKYIL

Ligand information

>3e3y Chain E (length=14) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

gccggttaaccggc

Receptor-Ligand Complex Structure

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Structure summary

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PDB	3e3y DNA distortion and specificity in a sequence-specific endonuclease.
Resolution	2.13 Å
Binding residue (original residue number in PDB)	G92 K93 F138 Y199 N201 A203 R241
Binding residue (residue number reindexed from 1)	G77 K78 F122 Y183 N185 A187 R225

Enzymatic activity

Enzyme Commision number

3.1.21.4: type II site-specific deoxyribonuclease.

Gene Ontology

	Molecular Function
GO:0003677	DNA binding
GO:0004519	endonuclease activity
GO:0009036	type II site-specific deoxyribonuclease activity

	Biological Process
GO:0009307	DNA restriction-modification system

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Molecular Function

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Biological Process

External links

PDB	RCSB:3e3y, PDBe:3e3y, PDBj:3e3y
PDBsum	3e3y
PubMed	18762194
UniProt	P17743\|T2C2_HAEIF Type II restriction enzyme HincII (Gene Name=hincIIR)

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