Structure of PDB 3e2e Chain A Binding Site BS01

Receptor Information
>3e2e Chain A (length=832) Species: 10760 (Escherichia phage T7) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KNDFSDIELAAIPFNTLADHYGERLAREQLALEHESYEMGEARFRKMFER
LITTLLPKMIARINDWFEEVKAKRGKRPTAFQFLQEIKPEAVAYITIKTT
LACLTSADNTTVQAVASAIGRAIEDEARFGRIRDLEAKHFKKNVYKKAFM
QVVEADMLSKGLLGGEAWSSWHKEDSIHVGVRCIEMLIESTGMVSLHRQN
AGVVGQDSETIELAPEYAEAIISLMFQPCVVPPKPWTGITGGGYWANGRR
PLALVRTHSKKALMRYEDVYMPEVYKAINIAQNTAWKINKKVLAVANVIT
KWKHCPVEDIPAIEREELPMKPDMNPEALTAWKRAAAAVYRKDKARKSRR
ISLEFMLEQANKFANHKAIWFPYNMDWRGRVYAVSMFNPQGNDMTKGLLT
LAKGKPIGKEGYYWLKIHGANCAGVDKVPFPERIKFIEENHENIMACAKS
PLENTWWAEQDSPFCFLAFCFEYAGVQHHGLSYNCSLPLAFDGSCSGIQH
FSAMLRDEVGGRAVNLLPSETVQDIYGIVAKKVNEILQADAINGTDNEVV
TVTISEKVKLGTKALAGQWLAYGVTRSVTKRSVMTLAYGSKEFGFRQQVL
EDTIQPAIDSGKGLMFTQPNQAAGYMAKLIWESVSVTVVAAVEAMNWLKS
AAKLLAAEVKDKKTGEILRKRCAVHWVTPDGFPVWQEYKKPIQTRLNLMF
LGQFRLQPTINTNKDSEIDAHKQESGIAPNFVHSQDGSHLRKTVVWAHEK
YGIESFALIHDSFGTIPADAANLFKAVRETMVDTYESCDVLADFYDQFAD
QLHESQLDKMPALPAKGNLNLRDILESDFAFA
Ligand information
Receptor-Ligand Complex Structure
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PDB3e2e The structure of a transcribing t7 RNA polymerase in transition from initiation to elongation
Resolution3.0 Å
Binding residue
(original residue number in PDB)		K389 S393 R394 N437 R632 Y639 D812
Binding residue
(residue number reindexed from 1)		K344 S348 R349 N392 R581 Y588 D761
Enzymatic activity
Enzyme Commision number 2.7.7.6: DNA-directed RNA polymerase.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003899 DNA-directed 5'-3' RNA polymerase activity
GO:0016779 nucleotidyltransferase activity
GO:0034062 5'-3' RNA polymerase activity
Biological Process
GO:0006351 DNA-templated transcription
GO:0019083 viral transcription
GO:0039695 DNA-templated viral transcription
Cellular Component
GO:0000428 DNA-directed RNA polymerase complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3e2e, PDBe:3e2e, PDBj:3e2e
PDBsum3e2e
PubMed18948533
UniProtP00573|RPOL_BPT7 T7 RNA polymerase (Gene Name=1)

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