Structure of PDB 3dxa Chain A Binding Site BS01

Receptor Information
>3dxa Chain A (length=276) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSHSMRYFYTAMSRPGRGEPRFITVGYVDDTLFVRFDSDATSPRKEPRAP
WIEQEGPEYWDRETQISKTNTQTYRENLRTALRYYNQSEAGSHIIQRMYG
CDVGPDGRLLRGYDQYAYDGKDYIALNEDLSSWTAADTAAQITQRKWEAA
RVAEQDRAYLEGLCVESLRRYLENGKETLQRADPPKTHVTHHPISDHEVT
LRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVP
SGEEQRYTCHVQHEGLPKPLTLRWEP
Ligand information
>3dxa Chain C (length=10) Species: 10377 (Human herpesvirus 4 strain B95-8) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
EENLLDFVRF
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB3dxa Natural micropolymorphism in human leukocyte antigens provides a basis for genetic control of antigen recognition.
Resolution3.5 Å
Binding residue
(original residue number in PDB)
Y7 Y9 K45 Y59 R62 E63 I66 N70 N77 T80 Y99 Y123 T143 W147 Q155 Y159 L163 S167 Y171
Binding residue
(residue number reindexed from 1)
Y7 Y9 K45 Y59 R62 E63 I66 N70 N77 T80 Y99 Y123 T143 W147 Q155 Y159 L163 S167 Y171
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:3dxa, PDBe:3dxa, PDBj:3dxa
PDBsum3dxa
PubMed19139173
UniProtP01889|HLAB_HUMAN HLA class I histocompatibility antigen, B alpha chain (Gene Name=HLA-B)

[Back to BioLiP]