Structure of PDB 3dx8 Chain A Binding Site BS01

Receptor Information
>3dx8 Chain A (length=276) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSHSMRYFYTAMSRPGRGEPRFITVGYVDDTLFVRFDSDATSPRKEPRAP
WIEQEGPEYWDRETQISKTNTQTYRENLRTALRYYNQSEAGSHIIQRMYG
CDVGPDGRLLRGYDQYAYDGKDYIALNEDLSSWTAADTAAQITQRKWEAA
RVAEQDRAYLEGLCVESLRRYLENGKETLQRADPPKTHVTHHPISDHEVT
LRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVP
SGEEQRYTCHVQHEGLPKPLTLRWEP
Ligand information
>3dx8 Chain C (length=10) Species: 10377 (Human herpesvirus 4 strain B95-8) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
EENLLDFVRF
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3dx8 Natural micropolymorphism in human leukocyte antigens provides a basis for genetic control of antigen recognition.
Resolution2.1 Å
Binding residue
(original residue number in PDB)
Y7 Y9 K45 R62 E63 N77 Y84 I95 Y99 Y123 T143 K146 W147 D156 Y159 L163 S167 Y171
Binding residue
(residue number reindexed from 1)
Y7 Y9 K45 R62 E63 N77 Y84 I95 Y99 Y123 T143 K146 W147 D156 Y159 L163 S167 Y171
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:3dx8, PDBe:3dx8, PDBj:3dx8
PDBsum3dx8
PubMed19139173
UniProtP01889|HLAB_HUMAN HLA class I histocompatibility antigen, B alpha chain (Gene Name=HLA-B)

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