Structure of PDB 3dx6 Chain A Binding Site BS01

Receptor Information
>3dx6 Chain A (length=276) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSHSMRYFYTAMSRPGRGEPRFITVGYVDDTLFVRFDSDATSPRKEPRAP
WIEQEGPEYWDRETQISKTNTQTYRENLRTALRYYNQSEAGSHIIQRMYG
CDVGPDGRLLRGYDQDAYDGKDYIALNEDLSSWTAADTAAQITQRKWEAA
RVAEQDRAYLEGLCVESLRRYLENGKETLQRADPPKTHVTHHPISDHEVT
LRCWALGFYPAEITLTWQRDGEDQTQDTELVETRPAGDRTFQKWAAVVVP
SGEEQRYTCHVQHEGLPKPLTLRWEP
Ligand information
>3dx6 Chain C (length=10) Species: 10377 (Human herpesvirus 4 strain B95-8) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
EENLLDFVRF
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3dx6 Natural micropolymorphism in human leukocyte antigens provides a basis for genetic control of antigen recognition.
Resolution1.701 Å
Binding residue
(original residue number in PDB)
Y7 Y9 K45 E63 I66 T69 T73 N77 Y84 I95 Y99 Y123 T143 K146 W147 Q155 Y159 L163 S167 Y171
Binding residue
(residue number reindexed from 1)
Y7 Y9 K45 E63 I66 T69 T73 N77 Y84 I95 Y99 Y123 T143 K146 W147 Q155 Y159 L163 S167 Y171
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:3dx6, PDBe:3dx6, PDBj:3dx6
PDBsum3dx6
PubMed19139173
UniProtP01889|HLAB_HUMAN HLA class I histocompatibility antigen, B alpha chain (Gene Name=HLA-B)

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