Structure of PDB 3dtk Chain A Binding Site BS01

Receptor Information
>3dtk Chain A (length=247) Species: 310783 (Deinococcus deserti) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PTALAAAKARMRELAASYGAGLPGRDTHSLMHGLDGITLTFMPMGQRDGA
YDPEHHVILINSQVRPERQRFTLAHEISHALLLGDDDLLSDLHDEYEGDR
LEQVIETLCNVGAAALLMPAELIDDLLTRFGPTGRALAELARRADVSATS
ALYALAERTAPPVIYAVCALSRAKELTVRASSASAGVKYSLSAGTPVPDD
HPAALALDTRLPLAQDSYVPFRSGRRMPAYVDAFPERQRVLVSFALP
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain3dtk Chain A Residue 283 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3dtk Crystal structure of the IrrE protein, a central regulator of DNA damage repair in deinococcaceae
Resolution3.24 Å
Binding residue
(original residue number in PDB)		H82 E113
Binding residue
(residue number reindexed from 1)		H75 E106
Annotation score4
Enzymatic activity
Enzyme Commision number 3.4.24.-
Gene Ontology
Molecular Function
GO:0008237 metallopeptidase activity
GO:0046872 metal ion binding
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:3dtk, PDBe:3dtk, PDBj:3dtk
PDBsum3dtk
PubMed19150362
UniProtC1CZ84|IRRE_DEIDV Radiation response metalloprotease IrrE (Gene Name=irrE)

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