Structure of PDB 3dsc Chain A Binding Site BS01

Receptor Information
>3dsc Chain A (length=333) Species: 2261 (Pyrococcus furiosus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MKFAHLADIHLGYEQFHKPQREEEFAEAFKNALEIAVQENVDFILIAGDL
FHSSRPSPGTLKKAIALLQIPKEHSIPVFAIEGNHDRTQRGPSVLNLLED
FGLVYVIGMRKEKVENEYLTSERLGNGEYLVKGVYKDLEIHGMKYMSSAW
FEANKEILKRLFRPTDNAILMLHQGVREVSEARGEDYFEIGLGDLPEGYL
YYALGHIHKRYETSYSGSPVVYPGSLERWDFGDYEVRYEWDGIKFKERYG
VNKGFYIVEDFKPRFVEIKVRPFIDVKIKGSEEEIRKAIKRLIPLIPKNA
YVRLNIGWRKPFDLTEIKELLNVEYLKIDTWRI
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3dsc Mre11 dimers coordinate DNA end bridging and nuclease processing in double-strand-break repair.
Resolution2.7 Å
Binding residue
(original residue number in PDB)		Y13 E14 Q15 F16 H17 K18 P19 H52
Binding residue
(residue number reindexed from 1)		Y13 E14 Q15 F16 H17 K18 P19 H52
Enzymatic activity
Enzyme Commision number 3.1.-.-
Gene Ontology
Molecular Function
GO:0016787 hydrolase activity
Biological Process
GO:0000729 DNA double-strand break processing
GO:0006302 double-strand break repair

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Molecular Function
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Biological Process
External links
PDB RCSB:3dsc, PDBe:3dsc, PDBj:3dsc
PDBsum3dsc
PubMed18854158
UniProtQ8U1N9|MRE11_PYRFU DNA double-strand break repair protein Mre11 (Gene Name=mre11)

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