Structure of PDB 3d25 Chain A Binding Site BS01

Receptor Information
>3d25 Chain A (length=274) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAP
WIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYG
CDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAA
HVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEAT
LRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVP
SGQEQRYTCHVQHEGLPKPLTLRW
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3d25 Secondary anchor polymorphism in the HA-1 minor histocompatibility antigen critically affects MHC stability and TCR recognition
Resolution1.3 Å
Binding residue
(original residue number in PDB)
Y7 F9 E63 K66 V67 H70 T73 V76 D77 R97 Y99 T143 K146 W147 L156 Y159 W167 Y171
Binding residue
(residue number reindexed from 1)
Y7 F9 E63 K66 V67 H70 T73 V76 D77 R97 Y99 T143 K146 W147 L156 Y159 W167 Y171
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:3d25, PDBe:3d25, PDBj:3d25
PDBsum3d25
PubMed19234124
UniProtP04439|HLAA_HUMAN HLA class I histocompatibility antigen, A alpha chain (Gene Name=HLA-A)

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