Structure of PDB 3csq Chain A Binding Site BS01

Receptor Information
>3csq Chain A (length=324) Species: 2884424 (Bacillus phage phi29) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MVYVSNKYLTMSEMKVNAQYILNYLSSNGWTKQAICGMLGNMQSESTINP
GLWQNLDEGNTSLGFGLVQWTPASNYINWANSQGLPYKNMDSELKRIIWE
VNNNAQWINLRDMTFKEYIKSTKTPRELAMIFLASYERPANPNQPERGDQ
AEYWYKNLSLQLAQFPMDIINISQGENGSFSHKGTLCIDFVGKTEKYPYY
APCDCTCVWRGDASAYLAWTSDKEVMCADGSVRYITWVNVHESPLPFDVG
KKLKKGDLMGHTGIGGDHWHFNVIDGKEYQGWTKKPDSCLAGTELHIYDV
FAVNNVEIINGNGYDWKTSDWQDG
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain3csq Chain A Residue 335 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3csq Crystal and cryoEM structural studies of a cell wall degrading enzyme in the bacteriophage phi29 tail.
Resolution1.8 Å
Binding residue
(original residue number in PDB)		H188 D195 H280
Binding residue
(residue number reindexed from 1)		H182 D189 H270
Annotation score4
Enzymatic activity
Enzyme Commision number 3.2.1.-
3.4.-.-
Gene Ontology
Molecular Function
GO:0008237 metallopeptidase activity
GO:0016798 hydrolase activity, acting on glycosyl bonds
GO:0046872 metal ion binding
Biological Process
GO:0006508 proteolysis
GO:0031640 killing of cells of another organism
GO:0042742 defense response to bacterium
GO:0046718 symbiont entry into host cell
GO:0071555 cell wall organization
GO:0098003 viral tail assembly
GO:0098004 virus tail fiber assembly
GO:0098932 symbiont entry into host cell via disruption of host cell wall peptidoglycan
GO:0098994 symbiont entry into host cell via disruption of host cell envelope
GO:0099002 symbiont genome ejection through host cell envelope, short tail mechanism
Cellular Component
GO:0044423 virion component
GO:0098023 virus tail, tip

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3csq, PDBe:3csq, PDBj:3csq
PDBsum3csq
PubMed18606992
UniProtP15132|GP13_BPPH2 Morphogenesis protein 1 (Gene Name=13)

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