Structure of PDB 3cld Chain A Binding Site BS01
Receptor Information
>3cld Chain A (length=243) Species:
9606
(Homo sapiens) [
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PQLTPTLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTLNMLGGRQVIAAV
KWAKAIPGFRNLHLDDQMTLLQYSWMYLMAFALGWRSYRQNLLCFAPDLI
INEQRMTLPGMYDQCKHMLYVSSELHRLQVSYEEYLCMKTLLLLSSVPKD
GLKSQELFDEIRMTYIKELGKAIVKRQNWQRFYQLTKLLDSMHEVVENLL
NYCFQTFLDKTMSIEFPEMLAEIITNQIPKYSNGNIKKLLFHQ
Ligand information
>3cld Chain H (length=9) Species:
9606
(Homo sapiens) [
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NALLRYLLD
Receptor-Ligand Complex Structure
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PDB
3cld
X-ray crystal structure of the novel enhanced-affinity glucocorticoid agonist fluticasone furoate in the glucocorticoid receptor-ligand binding domain.
Resolution
2.84 Å
Binding residue
(original residue number in PDB)
V575 K579 L589 M593
Binding residue
(residue number reindexed from 1)
V50 K54 L64 M68
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:3cld
,
PDBe:3cld
,
PDBj:3cld
PDBsum
3cld
PubMed
18522385
UniProt
P04150
|GCR_HUMAN Glucocorticoid receptor (Gene Name=NR3C1)
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