Structure of PDB 3c5l Chain A Binding Site BS01
Receptor Information
>3c5l Chain A (length=217) Species:
9606
(Homo sapiens) [
Search protein sequence
] [
Download receptor structure
] [
Download structure with residue number starting from 1
] [
View receptor structure
]
HLSDMLQQLHSVNASKPSERGLVRQEEAEDPACIPIFWVSKWVDYSDKYG
LGYQLCDNSVGVLFNDSTRLILYNDGDSLQYIERDGTESYLTVSSHPNSL
MKKITLLKYFRNYMSEHLLKAGANITPREGRLPYLRTWFRTRSAIILHLS
NGSVQINFFQDHTKLILCPLMAAVTYIDEKRDFRTYRLSLLEEYGCCKEL
ASRLRYARTMVDKLLSS
Ligand information
>3c5l Chain B (length=5) [
Search peptide sequence
] [
Download ligand structure
] [
Download structure with residue number starting from 1
] [
View ligand structure
]
PPHST
Receptor-Ligand Complex Structure
Global view
Local view
Structure summary
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
PDB
3c5l
Structural and functional analyses of minimal phosphopeptides targeting the polo-box domain of polo-like kinase 1.
Resolution
2.33 Å
Binding residue
(original residue number in PDB)
K413 W414 D416 Y417 L490 L491 H538 K540
Binding residue
(residue number reindexed from 1)
K41 W42 D44 Y45 L118 L119 H162 K164
Enzymatic activity
Enzyme Commision number
2.7.11.21
: polo kinase.
External links
PDB
RCSB:3c5l
,
PDBe:3c5l
,
PDBj:3c5l
PDBsum
3c5l
PubMed
19597481
UniProt
P53350
|PLK1_HUMAN Serine/threonine-protein kinase PLK1 (Gene Name=PLK1)
[
Back to BioLiP
]
