Structure of PDB 3c5j Chain A Binding Site BS01

Receptor Information
>3c5j Chain A (length=178) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EEHVIIQAEFYLNPDQSGEFMFDFDGDEIFHVDMAKKETVWRLEEFGRFA
SFEAQGALANIAVDKANLEIMTKRSNYTPITNVPPEVTVLTNSPVELREP
NVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHLFRKFHYLP
FLPSTEDVYDCRVEHWGLDEPLLKHWEF
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3c5j The structure of HLA-DR52c: comparison to other HLA-DRB3 alleles.
Resolution1.8 Å
Binding residue
(original residue number in PDB)
Q9 A52 S53 G58 N62 V65 N69 I72 M73 R76
Binding residue
(residue number reindexed from 1)
Q7 A50 S51 G56 N60 V63 N67 I70 M71 R74
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0042613 MHC class II protein complex

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Biological Process

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Cellular Component
External links
PDB RCSB:3c5j, PDBe:3c5j, PDBj:3c5j
PDBsum3c5j
PubMed18697946
UniProtP01903|DRA_HUMAN HLA class II histocompatibility antigen, DR alpha chain (Gene Name=HLA-DRA)

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