Structure of PDB 3c3s Chain A Binding Site BS01
Receptor Information
>3c3s Chain A (length=196) Species:
9606
(Homo sapiens) [
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KHSLPDLPYDYGALEPHINAQIMQLHHSKHHAAYVNNLNVTEEKYQEALA
KGDVTAQIALQPALKFNGGGHINHSIFWTNLSPNGGGEPKGELLEAIKRD
FGSFDKFKEKLTAASVGVQGSGWGWLGFNKERGHLQIAACPNQDPLQGTT
GLIPLLGIDVWAHAYYLQYKNVRPDYLKAIWNVINWENVTERYMAC
Ligand information
Ligand ID
MN
InChI
InChI=1S/Mn/q+2
InChIKey
WAEMQWOKJMHJLA-UHFFFAOYSA-N
SMILES
Software
SMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Mn+2]
CACTVS 3.341
[Mn++]
Formula
Mn
Name
MANGANESE (II) ION
ChEMBL
DrugBank
DB06757
ZINC
PDB chain
3c3s Chain A Residue 199 [
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Receptor-Ligand Complex Structure
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PDB
3c3s
Role of a glutamate bridge spanning the dimeric interface of human manganese superoxide dismutase.
Resolution
2.5 Å
Binding residue
(original residue number in PDB)
H26 H74 D159 H163
Binding residue
(residue number reindexed from 1)
H26 H74 D159 H163
Annotation score
1
Enzymatic activity
Enzyme Commision number
1.15.1.1
: superoxide dismutase.
Gene Ontology
Molecular Function
GO:0004784
superoxide dismutase activity
GO:0046872
metal ion binding
Biological Process
GO:0006801
superoxide metabolic process
View graph for
Molecular Function
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Biological Process
External links
PDB
RCSB:3c3s
,
PDBe:3c3s
,
PDBj:3c3s
PDBsum
3c3s
PubMed
18373354
UniProt
P04179
|SODM_HUMAN Superoxide dismutase [Mn], mitochondrial (Gene Name=SOD2)
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