Structure of PDB 3c3r Chain A Binding Site BS01

Receptor Information

>3c3r Chain A (length=357) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

ATFISVQLKKTSEVDLAKPLVKFIQQTYPSGGEEQAQYCRAAEELSKLRR
AAVGRPLDKHEGALETLLRYYDQICSIEPKFPFSENQICLTFTWKDAFDK
GSLFGGSVKLALASLGYEKSCVLFNCAALASQIAAEQNLDNDEGLKIAAK
HYQFASGAFLHIKETVLSALSREPTVDISPDTVGTLSLIMLAQAQEVFFL
KATRDKMKDAIIAKLANQAADYFGDAFKQCQYKDTLPKEVFPVLAAKHCI
MQANAEYHQSILAKQQKKFGEEIARLQHAAELIKTVASRYDEYVNVKDFS
DKINRALAAAKKDNDFIYHDRVPDLKDLDPIGKATLVKSTPVNVPISQKF
TDLFEKM

Ligand information

>3c3r Chain B (length=13) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

EDDDIKQLAAWAT

Receptor-Ligand Complex Structure

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Structure summary

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PDB	3c3r ALIX-CHMP4 interactions in the human ESCRT pathway.
Resolution	2.02 Å
Binding residue (original residue number in PDB)	D143 K147 F199 K202 M208 I212 L337
Binding residue (residue number reindexed from 1)	D142 K146 F198 K201 M207 I211 L336

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Biological Process
GO:0071985	multivesicular body sorting pathway

View graph for
Biological Process

External links

PDB	RCSB:3c3r, PDBe:3c3r, PDBj:3c3r
PDBsum	3c3r
PubMed	18511562
UniProt	Q8WUM4\|PDC6I_HUMAN Programmed cell death 6-interacting protein (Gene Name=PDCD6IP)

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