Structure of PDB 3c25 Chain A Binding Site BS01

Receptor Information
>3c25 Chain A (length=354) Species: 1823 (Nocardia otitidiscaviarum) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ANFIAEFFGHRVYPEVVSTEAARNDQATGTCPFLTAAKLVETSCVKAETS
RGVCVVNTAVDNERYDWLVCPNRALDPLFMSAASRKLFGYGPTEPLQFIA
APTLADQAVRDGIREWLDRGVHVVAYFQEKLGGELSISKTDSSPEFSFDW
TLAEVESIYPVPKIKRYGVLEIQTMDFHGSYKHAVGAIDIALVEGIDFHG
WLPTPAGRAALSKKMEGPNLSNVFKRTFYQMAYKFALSGHQRCAGTGFAI
PQSVWKSWLRHLANPTLIDNGDGTFSLGDTRNDSENAWIFVFELDPDTDA
SPRPLAPHLEIRVNVDTLIDLALRESPRAALGPSGPVATFTDKVEARMLR
FWPK
Ligand information
Receptor-Ligand Complex Structure
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PDB3c25 Structures of the Rare-Cutting Restriction Endonuclease NotI Reveal a Unique Metal Binding Fold Involved in DNA Binding.
Resolution2.5 Å
Binding residue
(original residue number in PDB)
N13 K141 E145 H189 N230 S232 K236
Binding residue
(residue number reindexed from 1)
N2 K130 E134 H178 N219 S221 K225
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity
GO:0042802 identical protein binding
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:3c25, PDBe:3c25, PDBj:3c25
PDBsum3c25
PubMed18400177
UniProtQ2I6W2

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