Structure of PDB 3c0q Chain A Binding Site BS01

Receptor Information
>3c0q Chain A (length=277) Species: 274 (Thermus thermophilus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MIRLGYPCENLTLGATTNRTLRLAHLTEERVREKAAENLRDLERILRFNA
DHGFALFRIGQHLIPFASHPLFPYDWEGAYEEELARLGALARAFGQRLSM
HPGQYVNPGSPDPEVVERSLAELRYSARLLSLLGAEDGVLVLHLGGAYGE
KGKALRRFVENLRGEEEVLRYLALANDERLWNVEEVLKAAEALGVPVVVD
TLHHALNPGRLPLEEALRLAFPTWRGRPKVHLASQDPKKRPGAHAFRVTR
EDWERLLSALPGPADVMVEAKGKEQGL
Ligand information
Ligand IDMN
InChIInChI=1S/Mn/q+2
InChIKeyWAEMQWOKJMHJLA-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mn+2]
CACTVS 3.341[Mn++]
FormulaMn
NameMANGANESE (II) ION
ChEMBL
DrugBankDB06757
ZINC
PDB chain3c0q Chain A Residue 283 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3c0q Involvement of a carboxylated lysine in UV damage endonuclease
Resolution2.74 Å
Binding residue
(original residue number in PDB)		H203 H244
Binding residue
(residue number reindexed from 1)		H203 H244
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity
GO:0046872 metal ion binding
Biological Process
GO:0006281 DNA repair
GO:0006289 nucleotide-excision repair
GO:0009411 response to UV

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Molecular Function
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Biological Process
External links
PDB RCSB:3c0q, PDBe:3c0q, PDBj:3c0q
PDBsum3c0q
PubMed19241382
UniProtQ746K1

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