Structure of PDB 3bzf Chain A Binding Site BS01
Receptor Information
>3bzf Chain A (length=276) Species:
9606
(Homo sapiens) [
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GSHSLKYFHTSVSRPGRGEPRFISVGYVDDTQFVRFDNDAASPRMVPRAP
WMEQEGSEYWDRETRSARDTAQIFRVNLRTLRGYYNQSEAGSHTLQWMHG
CELGPDRRFLRGYEQFAYDGKDYLTLNEDLRSWTAVDTAAQISEQKSNDA
SEAEHQRAYLEDTCVEWLHKYLEKGKETLLHLEPPKTHVTHHPISDHEAT
LRCWALGFYPAEITLTWQQDGEGHTQDTELVETRPAGDGTFQKWAAVVVP
SGEEQRYTCHVQHEGLPEPVTLRWKP
Ligand information
>3bzf Chain P (length=9) Species:
9606
(Homo sapiens) [
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VMAPRALLL
Receptor-Ligand Complex Structure
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PDB
3bzf
Subtle changes in peptide conformation profoundly affect recognition of the non-classical MHC class I molecule HLA-E by the CD94-NKG2 natural killer cell receptors
Resolution
2.5 Å
Binding residue
(original residue number in PDB)
Y7 E63 S66 A67 I73 N77 L81 Y84 W97 H99 W133 S143 K146 E152 Q156 Y159 W167 Y171
Binding residue
(residue number reindexed from 1)
Y7 E63 S66 A67 I73 N77 L81 Y84 W97 H99 W133 S143 K146 E152 Q156 Y159 W167 Y171
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:3bzf
,
PDBe:3bzf
,
PDBj:3bzf
PDBsum
3bzf
PubMed
18339401
UniProt
P13747
|HLAE_HUMAN HLA class I histocompatibility antigen, alpha chain E (Gene Name=HLA-E)
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