Structure of PDB 3bze Chain A Binding Site BS01
Receptor Information
>3bze Chain A (length=273) Species:
9606
(Homo sapiens) [
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SHSLKYFHTSVSRPGRGEPRFISVGYVDDTQFVRFDNDAASPRMVPRAPW
MEQEGSEYWDRETRSARDTAQIFRVNLRTLRGYYNQSEAGSHTLQWMHGC
ELGPDRRFLRGYEQFAYDGKDYLTLNEDLRSWTAVDTAAQISEQKSNDAS
EAEHQRAYLEDTCVEWLHKYLEKGKETLLHLEPPKTHVTHHPISDHEATL
RCWALGFYPAEITLTWQQDGEGHTQDTELVETRPAGDGTFQKWAAVVVPS
GEEQRYTCHVQHEGLPEPVTLRW
Ligand information
>3bze Chain P (length=9) Species:
9606
(Homo sapiens) [
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VMAPRTLFL
Receptor-Ligand Complex Structure
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PDB
3bze
Subtle changes in peptide conformation profoundly affect recognition of the non-classical MHC class I molecule HLA-E by the CD94-NKG2 natural killer cell receptors
Resolution
2.5 Å
Binding residue
(original residue number in PDB)
Y7 H9 E63 S66 A67 I73 F74 N77 Y84 W97 H99 L124 W133 S143 K146 E152 H155 Q156 Y159 W167 Y171
Binding residue
(residue number reindexed from 1)
Y6 H8 E62 S65 A66 I72 F73 N76 Y83 W96 H98 L123 W132 S142 K145 E151 H154 Q155 Y158 W166 Y170
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:3bze
,
PDBe:3bze
,
PDBj:3bze
PDBsum
3bze
PubMed
18339401
UniProt
P13747
|HLAE_HUMAN HLA class I histocompatibility antigen, alpha chain E (Gene Name=HLA-E)
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