Structure of PDB 3buc Chain A Binding Site BS01

Receptor Information
>3buc Chain A (length=200) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SWRHIRAEGLDSSYTVLFGKAEADEIFQELEKEVEYFTGALARVQVFGKW
HSVPRKQATYGDAGLTYTFSGLTLSPKPWIPVLERIRDHVSGVTGQTFNF
VLINRYKDGSDHICEHRDDERELAPGSPIASVSFGASRDFVFRHKDSRPS
RRVAVVRLPLAHGSLLMMNHPTNTHWYHSLPVRKKVLAPRVNLTFRKILL
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3buc Crystal structures of DNA/RNA repair enzymes AlkB and ABH2 bound to dsDNA.
Resolution2.59 Å
Binding residue
(original residue number in PDB)		V101 F102 H106 R110 Y122 F124 S125 I168 C169 H171 E175 Y235 R254
Binding residue
(residue number reindexed from 1)		V46 F47 H51 R55 Y67 F69 S70 I113 C114 H116 E120 Y177 R196
Enzymatic activity
Enzyme Commision number 1.14.11.33: DNA oxidative demethylase.
Gene Ontology

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Biological Process
External links
PDB RCSB:3buc, PDBe:3buc, PDBj:3buc
PDBsum3buc
PubMed18432238
UniProtQ6NS38|ALKB2_HUMAN DNA oxidative demethylase ALKBH2 (Gene Name=ALKBH2)

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