Structure of PDB 3bu0 Chain A Binding Site BS01

Receptor Information
>3bu0 Chain A (length=203) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SWRHIRAEGLDSSYTVLFGKAEADEIFQELEKEVEYFTGALARVQVFGKW
HSVPRKQATYGDAGLTYTFSGLTLSPKPWIPVLERIRDHVSGVTGQTFNF
VLINRYKDGSDHIGEHRDDCRELAPGSPIASVSFGASRDFVFRHKDSRGK
SPSRRVAVVRLPLAHGSLLMMNHPTNTHWYHSLPVRKKVLAPRVNLTFRK
ILL
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3bu0 Crystal structures of DNA/RNA repair enzymes AlkB and ABH2 bound to dsDNA.
Resolution2.5 Å
Binding residue
(original residue number in PDB)		V101 F102 H106 P109 R110 Y122 F124 S125 H167 I168 G169 H171 C175 Y235
Binding residue
(residue number reindexed from 1)		V46 F47 H51 P54 R55 Y67 F69 S70 H112 I113 G114 H116 C120 Y180
Enzymatic activity
Enzyme Commision number 1.14.11.33: DNA oxidative demethylase.
Gene Ontology

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Biological Process
External links
PDB RCSB:3bu0, PDBe:3bu0, PDBj:3bu0
PDBsum3bu0
PubMed18432238
UniProtQ6NS38|ALKB2_HUMAN DNA oxidative demethylase ALKBH2 (Gene Name=ALKBH2)

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