Structure of PDB 3btz Chain A Binding Site BS01

Receptor Information
>3btz Chain A (length=202) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
WRHIRAEGLDSSYTVLFGKAEADEIFQELEKEVEYFTGALARVQVFGKWH
SVPRKQATYGDAGLTYTFSGLTLSPKPWIPVLERIRDHVSGVTGQTFNFV
LINRYKDGSDHIGEHRDDCRELAPGSPIASVSFGASRDFVFRHKDSRGKS
PSRRVAVVRLPLAHGSLLMMNHPTNTHWYHSLPVRKKVLAPRVNLTFRKI
LL
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3btz Crystal structures of DNA/RNA repair enzymes AlkB and ABH2 bound to dsDNA.
Resolution3.0 Å
Binding residue
(original residue number in PDB)		V101 F102 H106 P109 R110 Y122 F124 S125 H167 I168 G169 E170 H171 C175 R203 Y235
Binding residue
(residue number reindexed from 1)		V45 F46 H50 P53 R54 Y66 F68 S69 H111 I112 G113 E114 H115 C119 R147 Y179
Enzymatic activity
Enzyme Commision number 1.14.11.33: DNA oxidative demethylase.
Gene Ontology

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Biological Process
External links
PDB RCSB:3btz, PDBe:3btz, PDBj:3btz
PDBsum3btz
PubMed18432238
UniProtQ6NS38|ALKB2_HUMAN DNA oxidative demethylase ALKBH2 (Gene Name=ALKBH2)

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