Structure of PDB 3bty Chain A Binding Site BS01

Receptor Information
>3bty Chain A (length=200) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SWRHIRAEGLDSSYTVLFGKAEADEIFQELEKEVEYFTGALARVQVFGKW
HSVPRKQATYGDAGLTYTFSGLTLSPKPWIPVLERIRDHVSGVTGQTFNF
VLINRYKDGSDHICEHRDDERELAPGSPIASVSFGASRDFVFRHKDSRPS
RRVAVVRLPLAHGSLLMMNHPTNTHWYHSLPVRKKVLAPRVNLTFRKILL
Ligand information
Receptor-Ligand Complex Structure
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PDB3bty Crystal structures of DNA/RNA repair enzymes AlkB and ABH2 bound to dsDNA.
Resolution2.35 Å
Binding residue
(original residue number in PDB)
V101 F102 H106 R110 Y122 F124 S125 H167 I168 C169 H171 E175 Y235
Binding residue
(residue number reindexed from 1)
V46 F47 H51 R55 Y67 F69 S70 H112 I113 C114 H116 E120 Y177
Enzymatic activity
Enzyme Commision number 1.14.11.33: DNA oxidative demethylase.
Gene Ontology

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Biological Process
External links
PDB RCSB:3bty, PDBe:3bty, PDBj:3bty
PDBsum3bty
PubMed18432238
UniProtQ6NS38|ALKB2_HUMAN DNA oxidative demethylase ALKBH2 (Gene Name=ALKBH2)

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