Structure of PDB 3bsn Chain A Binding Site BS01

Receptor Information
>3bsn Chain A (length=479) Species: 11983 (Norwalk virus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KGTYCGAPILGPGSAPKLSTKTKFWRSSTAPLPPGTYEPAYLGGKDPRVK
GGPSLQQVMRDQLKPFTEPRGKPPKPSVLEAAKKTIINVLEQTIDPPDKW
SFAQACASLDKTTSSGHPHHMRKNDCWNGESFTGKLADQASKANLMFEEG
KNMTPVYTGALKDELVKTDKIYGKIKKRLLWGSDLATMIRCARAFGGLMD
ELKTHCVTLPIRVGMNMNEDGPIIFERHSRYRYHYDADYSRWDSTQQRAV
LAAALEIMVKFSSEPHLAQVVAEDLLSPSVVDVGDFTISINEGLPSGVPC
TSQWNSIAHWLLTLCALSEVTNLSPDIIQANSLFSFYGDDEIVSTDIKLD
PEKLTAKLKEYGLKPTRPDKTEGPLVISEDLNGLTFLRRTVTRDPAGWFG
KLEQSSILRQMYWTRGPNHEDPSETMIPHSQRPIQLMSLLGEAALHGPAF
YSKISKLVIAELDFYVPRQEPMFRWMRFS
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3bsn Structural insights into mechanisms of catalysis and inhibition in norwalk virus polymerase.
Resolution1.8 Å
Binding residue
(original residue number in PDB)		T116 N128 S306 Y341 D344 L391 R392 L406 S410 Q414 R419
Binding residue
(residue number reindexed from 1)		T112 N124 S302 Y337 D340 L387 R388 L402 S406 Q410 R415
Enzymatic activity
Enzyme Commision number 3.4.22.66: calicivirin.
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003968 RNA-dependent RNA polymerase activity
GO:0004386 helicase activity
GO:0005524 ATP binding
Biological Process
GO:0006351 DNA-templated transcription
GO:0039694 viral RNA genome replication

View graph for
Molecular Function
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Biological Process
External links
PDB RCSB:3bsn, PDBe:3bsn, PDBj:3bsn
PDBsum3bsn
PubMed18184655
UniProtQ70ET3

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