Structure of PDB 3brf Chain A Binding Site BS01

Receptor Information

>3brf Chain A (length=423) Species: 6239 (Caenorhabditis elegans)

SLTSDRMIDFLSNKEKYECVISIFHAKVAQKSYGNEKRFFCPPPCIYLIG
QGWKLKKDRVAQLYKTLTELVAYIGIGSDTSERQQLDFPNIYDYCAAKTL
YISDSDKRKYFDLNAQFFYGCGMEIGGFVSQRIKVISKPSKKKQSDCKYL
CIASGTKVALFNRLRSQTVSTRYLHVEGNAFHASSTKWGAFTIHLFDDEQ
ETDNFAVRDGFVYYGSVVKLVDSVTGIALPRLRIRKVDKQQVILDASCSE
EPVSQLHKCAFQMIDNELVYLCLSHDKIIQHQATAINEHRHQINDGAAWT
IISTDKAEYRFFEAMGQVANPISPCPVVGSLEVDGHGEASRVELHGRDFK
PNLKVWFGATPVETTFRSEESLHCSIPPVSQVRNEQTHWMFTNRTTGDVE
VPISLVRDDGVVYSSGLTFSYKS

Ligand information

>3brf Chain B (length=15)

ttactgtgggaaaga

Receptor-Ligand Complex Structure

Structure summary

• PDB: 3brf RAM-induced Allostery Facilitates Assembly of a Notch Pathway Active Transcription Complex.
• Resolution: 2.47 Å
• Binding residue (original residue number in PDB): K233 R234 F235 K368 R397 S400 K476 K495
• Binding residue (residue number reindexed from 1): K37 R38 F39 K138 R163 S166 K239 K258
• Binding affinity: PDBbind-CN: Kd=2.05uM

Gene Ontology

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UnboundLocalError

Python 3.6.8: /usr/bin/python3 Fri Nov 22 05:36:25 2024

A problem occurred in a Python script. Here is the sequence of function calls leading up to the error, in the order they occurred.

 /var/www/html/BioLiP/pdb.cgi in <module>()

   1435     title=pdb2title(pdbid)

   1436     if bs.startswith("BS"):

=> 1437         pubmed,uniprot=display_interaction(pdbid,asym_id,bs,title)

   1438     else:

   1439         if lig3:

pubmed = '', uniprot = '', display_interaction = <function display_interaction>, pdbid = '3brf', asym_id = 'A', bs = 'BS01', title = 'RAM-induced Allostery Facilitates Assembly of a Notch Pathway Active Transcription Complex.'

 /var/www/html/BioLiP/pdb.cgi in display_interaction(pdbid='3brf', asym_id='A', bs='BS01', title='RAM-induced Allostery Facilitates Assembly of a Notch Pathway Active Transcription Complex.')

   1295         display_ec(ec,csaOrig,csaRenu)

   1296     if go:

=> 1297         display_go(go,uniprot,pdbid,asym_id)

   1298     return pubmed,uniprot

   1299 

global display_go = <function display_go>, go = '0000978,0001228,0003677,0003700,0005634,0006355,0006357', uniprot = '', pdbid = '3brf', asym_id = 'A'

 /var/www/html/BioLiP/pdb.cgi in display_go(go='0000978,0001228,0003677,0003700,0005634,0006355,0006357', uniprot='', pdbid='3brf', asym_id='A')

    480         '''.replace("$namespace_link",namespace_link

    481           ).replace("$namespace",namespace

=>  482           ).replace("$uniprot",u

    483         ))

    484         for l,(term,name) in enumerate(go2aspect[Aspect]):

u undefined

UnboundLocalError: local variable 'u' referenced before assignment
      args = ("local variable 'u' referenced before assignment",)
      with_traceback = <built-in method with_traceback of UnboundLocalError object>