Structure of PDB 3bef Chain A Binding Site BS01

Receptor Information
>3bef Chain A (length=44) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SEYQTFFNPRTFGSGEADCGLRPLFEKKSLEDKTERELLESYID
Ligand information
Receptor-Ligand Complex Structure
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PDB3bef Structural identification of the pathway of long-range communication in an allosteric enzyme.
Resolution2.2 Å
Binding residue
(original residue number in PDB)		S14I Y14J D14L
Binding residue
(residue number reindexed from 1)		S41 Y42 D44
Enzymatic activity
Enzyme Commision number 3.4.21.5: thrombin.
Gene Ontology
Molecular Function
GO:0004252 serine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis
GO:0007596 blood coagulation
Cellular Component
GO:0005576 extracellular region

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Biological Process
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Cellular Component
External links
PDB RCSB:3bef, PDBe:3bef, PDBj:3bef
PDBsum3bef
PubMed18250335
UniProtP00734|THRB_HUMAN Prothrombin (Gene Name=F2)

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